Development of a Premature Stop Codon-detection method based on a bacterial two-hybrid system

BACKGROUND: The detection of Premature Stop Codons (PSCs) in human genes is very useful for the genetic diagnosis of different hereditary cancers, e.g. Familial Breast Cancer and Hereditary Non-Polyposis Colorectal Cancer (HNPCC). The products of these PSCs are truncated proteins, detectable in vitr...

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Detalles Bibliográficos
Autores principales: Real, Sebastián M, Marzese, Diego M, Gomez, Laura C, Mayorga, Luis S, Roqué, María
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569827/
https://www.ncbi.nlm.nih.gov/pubmed/16948859
http://dx.doi.org/10.1186/1472-6750-6-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569827/
https://www.ncbi.nlm.nih.gov/pubmed/16948859
http://dx.doi.org/10.1186/1472-6750-6-38

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