Effects of disrupting the polyketide synthase gene WdPKS1 in Wangiella [Exophiala] dermatitidis on melanin production and resistance to killing by antifungal compounds, enzymatic degradation, and extremes in temperature

BACKGROUND: Wangiella dermatitidis is a human pathogenic fungus that is an etiologic agent of phaeohyphomycosis. W. dermatitidis produces a black pigment that has been identified as a dihydroxynaphthalene melanin and the production of this pigment is associated with its virulence. Cell wall pigmenta...

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Detalles Bibliográficos
Autores principales: Paolo, William F, Dadachova, Ekaterina, Mandal, Piyali, Casadevall, Arturo, Szaniszlo, Paul J, Nosanchuk, Joshua D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569847/
https://www.ncbi.nlm.nih.gov/pubmed/16784529
http://dx.doi.org/10.1186/1471-2180-6-55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569847/
https://www.ncbi.nlm.nih.gov/pubmed/16784529
http://dx.doi.org/10.1186/1471-2180-6-55

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