Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio

BACKGROUND: Neuroblastoma (NB) is the second most common solid childhood tumour, an aggressive disease for which new therapeutic strategies are strongly needed. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis in most tumour cells, but not in normal tiss...

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Detalles Bibliográficos
Autores principales: Mühlethaler-Mottet, Annick, Flahaut, Marjorie, Bourloud, Katia Balmas, Auderset, Katya, Meier, Roland, Joseph, Jean-Marc, Gross, Nicole
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569857/
https://www.ncbi.nlm.nih.gov/pubmed/16930472
http://dx.doi.org/10.1186/1471-2407-6-214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569857/
https://www.ncbi.nlm.nih.gov/pubmed/16930472
http://dx.doi.org/10.1186/1471-2407-6-214

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