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Mapping of the methylation pattern of the hMSH2 promoter in colon cancer, using bisulfite genomic sequencing

The detailed methylation status of CpG sites in the promoter region of hMSH2 gene has yet not to be reported. We have mapped the complete methylation status of the hMSH2 promoter, a region that contains 75 CpG sites, using bisulfite genomic sequencing in 60 primary colorectal cancers. And the expres...

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Detalles Bibliográficos
Autores principales: Zhang, Hua, Fu, Wei-ling, Huang, Qing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570131/
https://www.ncbi.nlm.nih.gov/pubmed/16911791
http://dx.doi.org/10.1186/1477-3163-5-22