Cargando…

A maximum likelihood framework for protein design

BACKGROUND: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, this problem can also be understood in a wider context, where additional constraints are captured by learning the sequence p...

Descripción completa

Detalles Bibliográficos
Autores principales: Kleinman, Claudia L, Rodrigue, Nicolas, Bonnard, Cécile, Philippe, Hervé, Lartillot, Nicolas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570151/
https://www.ncbi.nlm.nih.gov/pubmed/16808841
http://dx.doi.org/10.1186/1471-2105-7-326