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Analysis of vaccinia virus temperature-sensitive I7L mutants reveals two potential functional domains

As an approach to initiating a structure-function analysis of the vaccinia virus I7L core protein proteinase, a collection of conditional-lethal mutants in which the mutation had been mapped to the I7L locus were subjected to genomic sequencing and phenotypic analyses. Mutations in six vaccinia viru...

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Detalles Bibliográficos
Autores principales: Moerdyk, Megan J, Byrd, Chelsea M, Hruby, Dennis E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570340/
https://www.ncbi.nlm.nih.gov/pubmed/16945137
http://dx.doi.org/10.1186/1743-422X-3-64