A protein evolution model with independent sites that reproduces site-specific amino acid distributions from the Protein Data Bank

BACKGROUND: Since thermodynamic stability is a global property of proteins that has to be conserved during evolution, the selective pressure at a given site of a protein sequence depends on the amino acids present at other sites. However, models of molecular evolution that aim at reconstructing the...

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Detalles Bibliográficos
Autores principales: Bastolla, Ugo, Porto, Markus, Roman, H Eduardo, Vendruscolo, Michele
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570368/
https://www.ncbi.nlm.nih.gov/pubmed/16737532
http://dx.doi.org/10.1186/1471-2148-6-43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570368/
https://www.ncbi.nlm.nih.gov/pubmed/16737532
http://dx.doi.org/10.1186/1471-2148-6-43

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