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A protein evolution model with independent sites that reproduces site-specific amino acid distributions from the Protein Data Bank
BACKGROUND: Since thermodynamic stability is a global property of proteins that has to be conserved during evolution, the selective pressure at a given site of a protein sequence depends on the amino acids present at other sites. However, models of molecular evolution that aim at reconstructing the...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570368/ https://www.ncbi.nlm.nih.gov/pubmed/16737532 http://dx.doi.org/10.1186/1471-2148-6-43 |