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Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change

BACKGROUND: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical screens. To advance biological knowledge, computational methods that can accurately detect ncRNAs in sequenced genomes are...

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Detalles Bibliográficos
Autores principales: Uzilov, Andrew V, Keegan, Joshua M, Mathews, David H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570369/
https://www.ncbi.nlm.nih.gov/pubmed/16566836
http://dx.doi.org/10.1186/1471-2105-7-173