Munc18-Bound Syntaxin Readily Forms SNARE Complexes with Synaptobrevin in Native Plasma Membranes

Munc18–1, a protein essential for regulated exocytosis in neurons and neuroendocrine cells, belongs to the family of Sec1/Munc18-like (SM) proteins. In vitro, Munc18–1 forms a tight complex with the SNARE syntaxin 1, in which syntaxin is stabilized in a closed conformation. Since closed syntaxin is...

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Detalles Bibliográficos
Autores principales: Zilly, Felipe E, Sørensen, Jakob B, Jahn, Reinhard, Lang, Thorsten
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570500/
https://www.ncbi.nlm.nih.gov/pubmed/17002520
http://dx.doi.org/10.1371/journal.pbio.0040330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570500/
https://www.ncbi.nlm.nih.gov/pubmed/17002520
http://dx.doi.org/10.1371/journal.pbio.0040330

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