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Genome sequence alterations detected upon passage of Burkholderia mallei ATCC 23344 in culture and in mammalian hosts

BACKGROUND: More than 12,000 simple sequence repeats (SSRs) have been identified in the genome of Burkholderia mallei ATCC 23344. As a demonstrated mechanism of phase variation in other pathogenic bacteria, these may function as mutable loci leading to altered protein expression or structure variati...

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Detalles Bibliográficos
Autores principales: Romero, Claudia M, DeShazer, David, Feldblyum, Tamara, Ravel, Jacques, Woods, Donald, Kim, H Stanley, Yu, Yan, Ronning, Catherine M, Nierman, William C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574311/
https://www.ncbi.nlm.nih.gov/pubmed/16953889
http://dx.doi.org/10.1186/1471-2164-7-228