Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation

BACKGROUND: DNA methylation and histone deacetylation are epigenetic mechanisms that play major roles in eukaryotic gene regulation. We hypothesize that many genes in the human hepatoma cell line HepG2 are regulated by DNA methylation and histone deacetylation. Treatment with 5-aza-2'-deoxycyti...

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Detalles Bibliográficos
Autores principales: Dannenberg, Luke O, Edenberg, Howard J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574318/
https://www.ncbi.nlm.nih.gov/pubmed/16854234
http://dx.doi.org/10.1186/1471-2164-7-181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574318/
https://www.ncbi.nlm.nih.gov/pubmed/16854234
http://dx.doi.org/10.1186/1471-2164-7-181

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