Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity

BACKGROUND: There is a large body of evidence which suggests that bile acids increase the risk of colon cancer and act as tumor promoters, however, the mechanism(s) of bile acids mediated tumorigenesis is not clear. Previously we showed that deoxycholic acid (DCA), a tumorogenic bile acid, and ursod...

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Detalles Bibliográficos
Autores principales: Powell, Ashley A, Akare, Sandeep, Qi, Wenqing, Herzer, Pascal, Jean-Louis, Samira, Feldman, Rebecca A, Martinez, Jesse D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574338/
https://www.ncbi.nlm.nih.gov/pubmed/16948850
http://dx.doi.org/10.1186/1471-2407-6-219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574338/
https://www.ncbi.nlm.nih.gov/pubmed/16948850
http://dx.doi.org/10.1186/1471-2407-6-219

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