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Heparin (GAG-hed) inhibits LCR activity of Human Papillomavirus type 18 by decreasing AP1 binding

BACKGROUND: High risk HPVs are causative agents of anogenital cancers. Viral E6 and E7 genes are continuously expressed and are largely responsible for the oncogenic activity of these viruses. Transcription of the E6 and E7 genes is controlled by the viral Long Control Region (LCR), plus several cel...

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Detalles Bibliográficos
Autores principales: Villanueva, Rita, Morales-Peza, Néstor, Castelán-Sánchez, Irma, García-Villa, Enrique, Tapia, Rocio, Cid-Arregui, Ángel, García-Carrancá, Alejandro, López-Bayghen, Esther, Gariglio, Patricio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574339/
https://www.ncbi.nlm.nih.gov/pubmed/16945153
http://dx.doi.org/10.1186/1471-2407-6-218