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The Influence of Recombination on Human Genetic Diversity

In humans, the rate of recombination, as measured on the megabase scale, is positively associated with the level of genetic variation, as measured at the genic scale. Despite considerable debate, it is not clear whether these factors are causally linked or, if they are, whether this is driven by the...

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Detalles Bibliográficos
Autores principales: Spencer, Chris C. A, Deloukas, Panos, Hunt, Sarah, Mullikin, Jim, Myers, Simon, Silverman, Bernard, Donnelly, Peter, Bentley, David, McVean, Gil
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575889/
https://www.ncbi.nlm.nih.gov/pubmed/17044736
http://dx.doi.org/10.1371/journal.pgen.0020148