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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

To restrict infection by Legionella pneumophila, mouse macrophages require Naip5, a member of the nucleotide-binding oligomerization domain leucine-rich repeat family of pattern recognition receptors, which detect cytoplasmic microbial products. We report that mouse macrophages restricted L. pneumop...

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Detalles Bibliográficos
Autores principales: Molofsky, Ari B., Byrne, Brenda G., Whitfield, Natalie N., Madigan, Cressida A., Fuse, Etsu T., Tateda, Kazuhiro, Swanson, Michele S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1584282/
https://www.ncbi.nlm.nih.gov/pubmed/16606669
http://dx.doi.org/10.1084/jem.20051659