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Dibenzazecine compounds with a novel dopamine/5HT(2A )receptor profile and 3D-QSAR analysis

BACKGROUND: Antipsychotics are divided into typical and atypical compounds based on clinical efficacy and side effects. The purpose of this study was to characterize in vitro a series of novel azecine-type compounds at human dopamine D(1)-D(5 )and 5HT(2A )receptors and to assign them to different cl...

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Detalles Bibliográficos
Autores principales: Hamacher, Alexandra, Weigt, Mathias, Wiese, Michael, Hoefgen, Barbara, Lehmann, Jochen, Kassack, Matthias U
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1586004/
https://www.ncbi.nlm.nih.gov/pubmed/16978403
http://dx.doi.org/10.1186/1471-2210-6-11