Predicting the effect of missense mutations on protein function: analysis with Bayesian networks

BACKGROUND: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, many of these methods break down if either one of the two types of data are missing. Furthermore, there is a lack of rigo...

Descripción completa

Detalles Bibliográficos
Autores principales: Needham, Chris J, Bradford, James R, Bulpitt, Andrew J, Care, Matthew A, Westhead, David R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1586217/
https://www.ncbi.nlm.nih.gov/pubmed/16956412
http://dx.doi.org/10.1186/1471-2105-7-405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1586217/
https://www.ncbi.nlm.nih.gov/pubmed/16956412
http://dx.doi.org/10.1186/1471-2105-7-405

Ejemplares similares