EGF-induced activation of Akt results in mTOR-dependent p70S6 kinase phosphorylation and inhibition of HC11 cell lactogenic differentiation

BACKGROUND: HC11 mouse mammary epithelial cells differentiate in response to lactogenic hormone resulting in expression of milk proteins including β-casein. Previous studies have shown that epidermal growth factor (EGF) blocks differentiation not only through activation of the Ras/Mek/Erk pathway bu...

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Detalles Bibliográficos
Autores principales: Galbaugh, Traci, Cerrito, Maria Grazia, Jose, Cynthia C, Cutler, Mary Lou
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1590014/
https://www.ncbi.nlm.nih.gov/pubmed/16984645
http://dx.doi.org/10.1186/1471-2121-7-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1590014/
https://www.ncbi.nlm.nih.gov/pubmed/16984645
http://dx.doi.org/10.1186/1471-2121-7-34

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