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Role of the unique N-terminal domain of CtBP2 in determining the subcellular localisation of CtBP family proteins

BACKGROUND: CtBP1 and CtBP2 are transcriptional co-repressors that modulate the activity of a large number of transcriptional repressors via the recruitment of chromatin modifiers. Many CtBP-regulated proteins are involved in pathways associated with tumorigenesis, including TGF-β and Wnt signalling...

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Detalles Bibliográficos
Autores principales: Bergman, Lee M, Morris, Laila, Darley, Matthew, Mirnezami, Alexander H, Gunatilake, Samal C, Blaydes, Jeremy P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592084/
https://www.ncbi.nlm.nih.gov/pubmed/16999872
http://dx.doi.org/10.1186/1471-2121-7-35