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Identification of sulfation sites of metabolites and prediction of the compounds’ biological effects

Characterizing the biological effects of metabolic transformations (or biotransformation) is one of the key steps in developing safe and effective pharmaceuticals. Sulfate conjugation, one of the major phase II biotransformations, is the focus of this study. While this biotransformation typically fa...

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Detalles Bibliográficos
Autores principales: Yi, Lin, Dratter, Joe, Wang, Chao, Tunge, Jon A., Desaire, Heather
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592252/
https://www.ncbi.nlm.nih.gov/pubmed/16724218
http://dx.doi.org/10.1007/s00216-006-0495-1