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Identification of sulfation sites of metabolites and prediction of the compounds’ biological effects
Characterizing the biological effects of metabolic transformations (or biotransformation) is one of the key steps in developing safe and effective pharmaceuticals. Sulfate conjugation, one of the major phase II biotransformations, is the focus of this study. While this biotransformation typically fa...
Autores principales: | Yi, Lin, Dratter, Joe, Wang, Chao, Tunge, Jon A., Desaire, Heather |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592252/ https://www.ncbi.nlm.nih.gov/pubmed/16724218 http://dx.doi.org/10.1007/s00216-006-0495-1 |
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