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A novel electron paramagnetic resonance-based assay for prostaglandin H synthase-1 activity
BACKGROUND: Prostaglandin H(2 )synthase (PGHS) is the enzyme that catalyses the two-stage conversion of arachidonic acid to prostaglandin H(2 )(PGH(2)) prior to formation of prostanoids that are important in inflammation. PGHS isozymes (-1 and -2) are the target for nonsteroidal anti-inflammatory dr...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592475/ https://www.ncbi.nlm.nih.gov/pubmed/17007643 http://dx.doi.org/10.1186/1476-9255-3-12 |