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Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias
T-cell acute lymphoblastic leukemia (T-ALL) is a high-risk type of blood-cell cancer. We describe the improvement of a candidate therapeutic virus for virotherapy of leukemic cells. Virotherapy is based on the exclusive replication of a virus in leukemic cells, leading to the selective removal of th...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592508/ https://www.ncbi.nlm.nih.gov/pubmed/17005036 http://dx.doi.org/10.1186/1742-4690-3-64 |