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A machine learning strategy to identify candidate binding sites in human protein-coding sequence

BACKGROUND: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR proteins, which are thought to mediate interactions between splicing factors bound to the 5' and 3' splice sites. It w...

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Detalles Bibliográficos
Autores principales: Down, Thomas, Leong, Bernard, Hubbard, Tim JP
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592515/
https://www.ncbi.nlm.nih.gov/pubmed/17002805
http://dx.doi.org/10.1186/1471-2105-7-419