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Hernia fibroblasts lack β-estradiol induced alterations of collagen gene expression

BACKGROUND: Estrogens are reported to increase type I and type III collagen deposition and to regulate Metalloproteinase 2 (MMP-2) expression. These proteins are reported to be dysregulated in incisional hernia formation resulting in a significantly decreased type I to III ratio. We aimed to evaluat...

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Detalles Bibliográficos
Autores principales: Jansen, Petra Lynen, Rosch, Raphael, Rezvani, Melanie, Mertens, Peter R, Junge, Karsten, Jansen, Marc, Klinge, Uwe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1594569/
https://www.ncbi.nlm.nih.gov/pubmed/17010202
http://dx.doi.org/10.1186/1471-2121-7-36