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Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with carcinogenesis
BACKGROUND: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several investigations support the view that common fragile sites play a role in carcinogenesis. We discuss a genome-wide approac...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1601973/ https://www.ncbi.nlm.nih.gov/pubmed/16981993 http://dx.doi.org/10.1186/1471-2105-7-413 |