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Inhibition of Interferon-γ Signaling in Oligodendroglia Delays Coronavirus Clearance without Altering Demyelination

Infection of the central nervous system (CNS) by the neurotropic JHM strain of mouse hepatitis virus (JHMV) induces an acute encephalomyelitis associated with demyelination. To examine the anti-viral and/or regulatory role of interferon-γ (IFN-γ) signaling in the cell that synthesizes and maintains...

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Detalles Bibliográficos
Autores principales: González, John M., Bergmann, Cornelia C., Ramakrishna, Chandran, Hinton, David R., Atkinson, Roscoe, Hoskin, Jason, Macklin, Wendy B., Stohlman, Stephen A.
Formato: Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1606538/
https://www.ncbi.nlm.nih.gov/pubmed/16507895
http://dx.doi.org/10.2353/ajpath.2006.050496