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Inhibition of Interferon-γ Signaling in Oligodendroglia Delays Coronavirus Clearance without Altering Demyelination
Infection of the central nervous system (CNS) by the neurotropic JHM strain of mouse hepatitis virus (JHMV) induces an acute encephalomyelitis associated with demyelination. To examine the anti-viral and/or regulatory role of interferon-γ (IFN-γ) signaling in the cell that synthesizes and maintains...
Autores principales: | González, John M., Bergmann, Cornelia C., Ramakrishna, Chandran, Hinton, David R., Atkinson, Roscoe, Hoskin, Jason, Macklin, Wendy B., Stohlman, Stephen A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Investigative Pathology
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1606538/ https://www.ncbi.nlm.nih.gov/pubmed/16507895 http://dx.doi.org/10.2353/ajpath.2006.050496 |
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