Activated AKT/PKB signaling in C. elegans uncouples temporally distinct outputs of DAF-2/insulin-like signaling

BACKGROUND: In the nematode, Caenorhabditis elegans, a conserved insulin-like signaling pathway controls larval development, stress resistance and adult lifespan. AGE-1, a homolog of the p110 catalytic subunit of phosphoinositide 3-kinases (PI3K) comprises the major known effector pathway downstream...

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Detalles Bibliográficos
Autores principales: Gami, Minaxi S, Iser, Wendy B, Hanselman, Keaton B, Wolkow, Catherine A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609106/
https://www.ncbi.nlm.nih.gov/pubmed/17020605
http://dx.doi.org/10.1186/1471-213X-6-45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609106/
https://www.ncbi.nlm.nih.gov/pubmed/17020605
http://dx.doi.org/10.1186/1471-213X-6-45

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