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Activated AKT/PKB signaling in C. elegans uncouples temporally distinct outputs of DAF-2/insulin-like signaling

BACKGROUND: In the nematode, Caenorhabditis elegans, a conserved insulin-like signaling pathway controls larval development, stress resistance and adult lifespan. AGE-1, a homolog of the p110 catalytic subunit of phosphoinositide 3-kinases (PI3K) comprises the major known effector pathway downstream...

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Detalles Bibliográficos
Autores principales:	Gami, Minaxi S, Iser, Wendy B, Hanselman, Keaton B, Wolkow, Catherine A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609106/ https://www.ncbi.nlm.nih.gov/pubmed/17020605 http://dx.doi.org/10.1186/1471-213X-6-45

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