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Molecular phylogeny of the antiangiogenic and neurotrophic serpin, pigment epithelium derived factor in vertebrates

BACKGROUND: Pigment epithelium derived factor (PEDF), a member of the serpin family, regulates cell proliferation, promotes survival of neurons, and blocks growth of new blood vessels in mammals. Defining the molecular phylogeny of PEDF by bioinformatic analysis is one approach to understanding the...

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Detalles Bibliográficos
Autores principales: Xu, Xuming, Zhang, Samuel Shao-Min, Barnstable, Colin J, Tombran-Tink, Joyce
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609119/
https://www.ncbi.nlm.nih.gov/pubmed/17020603
http://dx.doi.org/10.1186/1471-2164-7-248