Cytotoxic T cell recognition of an HIV-1 reverse transcriptase variant peptide incorporating the K103N drug resistance mutation

During HIV-1 infection, cytotoxic T cell (CTL) responses exert strong selective pressure on the replicating virus population. Here we report evidence for T cell activity against the drug resistant K103N region of viral reverse transcriptase in three HIV-1 infected patients exposed to NNRTI antiretro...

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Detalles Bibliográficos
Autores principales: Mahnke, Lisa, Clifford, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609176/
https://www.ncbi.nlm.nih.gov/pubmed/16970827
http://dx.doi.org/10.1186/1742-6405-3-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609176/
https://www.ncbi.nlm.nih.gov/pubmed/16970827
http://dx.doi.org/10.1186/1742-6405-3-21

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