Relevance of cyclin D1b expression and CCND1 polymorphism in the pathogenesis of multiple myeloma and mantle cell lymphoma

BACKGROUND: The CCND1 gene generates two mRNAs (cyclin D1a and D1b) through an alternative splicing at the site of a common A/G polymorphism. Cyclin D1a and b proteins differ in their C-terminus, a region involved in protein degradation and sub-cellular localization. Recent data have suggested that...

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Detalles Bibliográficos
Autores principales: Krieger, Sophie, Gauduchon, Juliette, Roussel, Mikel, Troussard, Xavier, Sola, Brigitte
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609182/
https://www.ncbi.nlm.nih.gov/pubmed/17022831
http://dx.doi.org/10.1186/1471-2407-6-238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609182/
https://www.ncbi.nlm.nih.gov/pubmed/17022831
http://dx.doi.org/10.1186/1471-2407-6-238

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