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Short-term arginine deprivation results in large-scale modulation of hepatic gene expression in both normal and tumor cells: microarray bioinformatic analysis

BACKGROUND: We have reported arginine-sensitive regulation of LAT1 amino acid transporter (SLC 7A5) in normal rodent hepatic cells with loss of arginine sensitivity and high level constitutive expression in tumor cells. We hypothesized that liver cell gene expression is highly sensitive to alteratio...

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Detalles Bibliográficos
Autores principales: Leong, Hwei Xian, Simkevich, Carl, Lesieur-Brooks, Anne, Lau, Bonnie W, Fugere, Celine, Sabo, Edmond, Thompson, Nancy L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1613245/
https://www.ncbi.nlm.nih.gov/pubmed/16961918
http://dx.doi.org/10.1186/1743-7075-3-37