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Limited proteolysis of human histone deacetylase 1

BACKGROUND: Histone deacetylase (HDAC) proteins are associated with cell proliferation, differentiation, apoptosis, and cancer. Specifically, HDAC1 is linked with cell growth, a hallmark of cancer formation. HDAC1 is a phosphoprotein and phosphorylation at S421 and S423 promotes HDAC1 enzymatic acti...

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Detalles Bibliográficos
Autores principales: Kamath, Nayana, Karwowska-Desaulniers, Paulina, Pflum, Mary Kay H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1613246/
https://www.ncbi.nlm.nih.gov/pubmed/17022812
http://dx.doi.org/10.1186/1471-2091-7-22