Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments

BACKGROUND: Molecular evolutionary studies of noncoding sequences rely on multiple alignments. Yet how multiple alignment accuracy varies across sequence types, tree topologies, divergences and tools, and further how this variation impacts specific inferences, remains unclear. RESULTS: Here we devel...

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Detalles Bibliográficos
Autores principales: Pollard, Daniel A, Moses, Alan M, Iyer, Venky N, Eisen, Michael B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1613255/
https://www.ncbi.nlm.nih.gov/pubmed/16904011
http://dx.doi.org/10.1186/1471-2105-7-376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1613255/
https://www.ncbi.nlm.nih.gov/pubmed/16904011
http://dx.doi.org/10.1186/1471-2105-7-376

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