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Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments
BACKGROUND: Molecular evolutionary studies of noncoding sequences rely on multiple alignments. Yet how multiple alignment accuracy varies across sequence types, tree topologies, divergences and tools, and further how this variation impacts specific inferences, remains unclear. RESULTS: Here we devel...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1613255/ https://www.ncbi.nlm.nih.gov/pubmed/16904011 http://dx.doi.org/10.1186/1471-2105-7-376 |