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Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas

BACKGROUND: Fascin is an actin bundling protein with roles in the formation of cell protrusions and motility of mesenchymal and neuronal cells. Fascin is normally low or absent from epithelia, but is upregulated in several epithelial neoplasms where it may contribute to an invasive phenotype. Here,...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yosuke, Skacel, Marek, Lavery, Ian C, Mukherjee, Abir L, Casey, Graham, Adams, Josephine C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615879/
https://www.ncbi.nlm.nih.gov/pubmed/17029629
http://dx.doi.org/10.1186/1471-2407-6-241