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Coordination of DNA synthesis and replicative unwinding by the S-phase checkpoint pathways

The process of DNA replication includes duplex unwinding, followed immediately by DNA synthesis. In eukaryotes, DNA synthesis is disturbed in damaged DNA regions, in replication slow zones, or as a result of insufficient nucleotide level. This review aims to discuss the mechanisms that coordinate DN...

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Detalles Bibliográficos
Autores principales: Nedelcheva-Veleva, Marina N., Krastev, Dragomir B., Stoynov, Stoyno S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1616944/
https://www.ncbi.nlm.nih.gov/pubmed/16935878
http://dx.doi.org/10.1093/nar/gkl528