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Methylene blue for malaria in Africa: results from a dose-finding study in combination with chloroquine

The development of safe, effective and affordable drug combinations against malaria in Africa is a public health priority. Methylene blue (MB) has a similar mode of action as chloroquine (CQ) and has moreover been shown to selectively inhibit the Plasmodium falciparum glutathione reductase. In 2004,...

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Detalles Bibliográficos
Autores principales: Meissner, Peter E, Mandi, Germain, Coulibaly, Boubacar, Witte, Steffen, Tapsoba, Théophile, Mansmann, Ulrich, Rengelshausen, Jens, Schiek, Wolfgang, Jahn, Albrecht, Walter-Sack, Ingeborg, Mikus, Gerd, Burhenne, Jürgen, Riedel, Klaus-Dieter, Schirmer, R Heiner, Kouyaté, Bocar, Müller, Olaf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617109/
https://www.ncbi.nlm.nih.gov/pubmed/17026773
http://dx.doi.org/10.1186/1475-2875-5-84