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From Bad to Good: Fitness Reversals and the Ascent of Deleterious Mutations

Deleterious mutations are considered a major impediment to adaptation, and there are straightforward expectations for the rate at which they accumulate as a function of population size and mutation rate. In a simulation model of an evolving population of asexually replicating RNA molecules, initiall...

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Detalles Bibliográficos
Autores principales: Cowperthwaite, Matthew C, Bull, J. J, Meyers, Lauren Ancel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617134/
https://www.ncbi.nlm.nih.gov/pubmed/17054393
http://dx.doi.org/10.1371/journal.pcbi.0020141