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From Bad to Good: Fitness Reversals and the Ascent of Deleterious Mutations
Deleterious mutations are considered a major impediment to adaptation, and there are straightforward expectations for the rate at which they accumulate as a function of population size and mutation rate. In a simulation model of an evolving population of asexually replicating RNA molecules, initiall...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617134/ https://www.ncbi.nlm.nih.gov/pubmed/17054393 http://dx.doi.org/10.1371/journal.pcbi.0020141 |