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Design of Phase II cancer trials evaluating survival probabilities

BACKGROUND: Phase II cancer studies are undertaken to assess the activity of a new drug or a new treatment regimen. Activity is sometimes defined in terms of a survival probability, a binary outcome such as one-year survival that is derived from a time-to-event variable. Phase II studies are usually...

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Detalles Bibliográficos
Autores principales: Case, L Douglas, Morgan, Timothy M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC161809/
https://www.ncbi.nlm.nih.gov/pubmed/12697051
http://dx.doi.org/10.1186/1471-2288-3-6