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A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus

In (+) RNA coronaviruses, replication and transcription of the giant ∼30 kb genome to produce genome- and subgenome-size RNAs of both polarities are mediated by a cognate membrane-bound enzymatic complex. Its RNA-dependent RNA polymerase (RdRp) activity appears to be supplied by non-structural prote...

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Detalles Bibliográficos
Autores principales: Imbert, Isabelle, Guillemot, Jean-Claude, Bourhis, Jean-Marie, Bussetta, Cécile, Coutard, Bruno, Egloff, Marie-Pierre, Ferron, François, Gorbalenya, Alexander E, Canard, Bruno
Formato: Texto
Lenguaje:English
Publicado: 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618104/
https://www.ncbi.nlm.nih.gov/pubmed/17024178
http://dx.doi.org/10.1038/sj.emboj.7601368