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A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus
In (+) RNA coronaviruses, replication and transcription of the giant ∼30 kb genome to produce genome- and subgenome-size RNAs of both polarities are mediated by a cognate membrane-bound enzymatic complex. Its RNA-dependent RNA polymerase (RdRp) activity appears to be supplied by non-structural prote...
Autores principales: | Imbert, Isabelle, Guillemot, Jean-Claude, Bourhis, Jean-Marie, Bussetta, Cécile, Coutard, Bruno, Egloff, Marie-Pierre, Ferron, François, Gorbalenya, Alexander E, Canard, Bruno |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618104/ https://www.ncbi.nlm.nih.gov/pubmed/17024178 http://dx.doi.org/10.1038/sj.emboj.7601368 |
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