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Gene function classification using Bayesian models with hierarchy-based priors

BACKGROUND: We investigate whether annotation of gene function can be improved using a classification scheme that is aware that functional classes are organized in a hierarchy. The classifiers look at phylogenic descriptors, sequence based attributes, and predicted secondary structure. We discuss th...

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Detalles Bibliográficos
Autores principales: Shahbaba, Babak, Neal, Radford M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618412/
https://www.ncbi.nlm.nih.gov/pubmed/17038174
http://dx.doi.org/10.1186/1471-2105-7-448