Target DNA Structure Plays a Critical Role in RAG Transposition

Antigen receptor gene rearrangements are initiated by the RAG1/2 protein complex, which recognizes specific DNA sequences termed RSS (recombination signal sequences). The RAG recombinase can also catalyze transposition: integration of a DNA segment bounded by RSS into an unrelated DNA target. For re...

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Detalles Bibliográficos
Autores principales: Posey, Jennifer E, Pytlos, Malgorzata J, Sinden, Richard R, Roth, David B
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618415/
https://www.ncbi.nlm.nih.gov/pubmed/17105341
http://dx.doi.org/10.1371/journal.pbio.0040350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618415/
https://www.ncbi.nlm.nih.gov/pubmed/17105341
http://dx.doi.org/10.1371/journal.pbio.0040350

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