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Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells
In eukaryotic cells, replication of genomic DNA initiates from multiple replication origins distributed on multiple chromosomes. To ensure that each origin is activated precisely only once during each S phase, a system has evolved which features periodic assembly and disassembly of essential pre-rep...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1621056/ https://www.ncbi.nlm.nih.gov/pubmed/17042960 http://dx.doi.org/10.1186/1747-1028-1-22 |