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Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2

BACKGROUND: The multi-step process of carcinogenesis can be more fully understood by characterizing gene expression changes induced in cells by carcinogens. In this study, expression microarrays were used to monitor the activity of 18,224 cDNA clones in MCF-7 and HepG2 cells exposed to the carcinoge...

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Detalles Bibliográficos
Autores principales: Hockley, Sarah L, Arlt, Volker M, Brewer, Daniel, Giddings, Ian, Phillips, David H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1621085/
https://www.ncbi.nlm.nih.gov/pubmed/17042939
http://dx.doi.org/10.1186/1471-2164-7-260