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Mathematical modeling of tumor therapy with oncolytic viruses: effects of parametric heterogeneity on cell dynamics

BACKGROUND: One of the mechanisms that ensure cancer robustness is tumor heterogeneity, and its effects on tumor cells dynamics have to be taken into account when studying cancer progression. There is no unifying theoretical framework in mathematical modeling of carcinogenesis that would account for...

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Detalles Bibliográficos
Autores principales: Karev, Georgy P, Novozhilov, Artem S, Koonin, Eugene V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1622743/
https://www.ncbi.nlm.nih.gov/pubmed/17018145
http://dx.doi.org/10.1186/1745-6150-1-30